Pierre Martinez

Pierre Martinez

Bioinformatics, Cancer Evolution

Selected Publications

  1. Coutant A […], Martinez P. Spatial Transcriptomics Reveal Pitfalls and Opportunities for the Detection of Rare High-Plasticity Breast Cancer Subtypes. Laboratory Investigation, 2023.
  2. Monteiro L […], Martinez P. Assessing Cell Activities rather than Identities to Interpret Intra-Tumor Phenotypic Diversity and Its Dynamics. iScience, 2020.
  3. Tokutomi N […], Martinez P. Quantifying local malignant adaptation in tissue‐specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level. Evolutionary Applications, 2019.
  4. Martinez P […], Maley CC. Evolution of Barrett’s Esophagus through space and time at single-crypt and whole-biopsy levels. Nature Communications, 2018.
  5. Martinez P […], Graham TA. Quantification of within-sample genetic heterogeneity from SNP-array data. Scientific Reports, 2017.
  6. Martinez P*, Timmer MR* […], Krishnadath KK. Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus. Nature Communications, 2016.
  7. Timmer MR*, Martinez P* […], Krishnadath KK. Derivation of genetic biomarkers for cancer risk stratification in Barrett’s Oesophagus: a prospective cohort study. Gut, 2015.
  8. Kanu N*, Grönroos E*, Martinez P* […], Swanton C. SETD2 loss of function promotes DNA replication stress and renal cancer genome instability. Oncogene, 2015.
  9. Martinez P […], Swanton C. Computational optimisation of targeted DNA sequencing for cancer detection. Scientific Reports, 2013.
  10. Martinez P* , Birkbak NJ*, Gerlinger M* […], Swanton C. Parallel evolution of tumor subclones mimics diversity between tumors. The Journal of Pathology, 2013.
  11. Gerlinger M*, Rowan AJ*, Horswell S*, Larkin J*, Endesfelder D*, Gronroos E*, Martinez P*, Matthews N*, Stewart A* […], Swanton C. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. New England Journal of Medicine, 2012.

Book chapters

  1. Martinez P, Graham T. Evolution and cancer. Why does Evolution Matter? The Importance of Understanding Evolution, Cambridge Scholars, 2014.

The full list is accessible on my Google Scholar profile.